Hspg2 CLIA Kit for Mouse(Mus musculus) | EIAab.comHspg2 CLIA Kit for Mouse(Mus musculus)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > Hspg2(Gene name) > Mouse

Hspg2 (Gene name),

Basement membrane-specific heparan sulfate proteoglycan core protein (Protein name ), PGBM_MOUSE from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

Hspg2;

Protein name:

Basement membrane-specific heparan sulfate proteoglycan core protein(HSPG);

Alternative:

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Purified perlecan has a strong tendency to aggregate in dimers or stellate structures. It interacts with other basement membrane components such as laminin, prolargin and collagen type IV. Interacts with COL13A1, FGFBP1 and VWA1. Interacts (via C-terminus) with ECM1 (via C-terminus).

Function:

The LG3 peptide has anti-angiogenic properties that require binding of calcium ions for full activity.

Subcellular Location:

Secreted extracellular space extracellular matrix basement membrane

Protein Attributes:

Sequence length:

3707

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

950:

1000:

1050:

1100:

1150:

1200:

1250:

1300:

1350:

1400:

1450:

1500:

1550:

1600:

1650:

1700:

1750:

1800:

1850:

1900:

1950:

2000:

2050:

2100:

2150:

2200:

2250:

2300:

2350:

2400:

2450:

2500:

2550:

2600:

2650:

2700:

2750:

2800:

2850:

2900:

2950:

3000:

3050:

3100:

3150:

3200:

3250:

3300:

3350:

3400:

3450:

3500:

3550:

3600:

3650:

3700:

3707:

NTRPCPS

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

Pfam:

PF00008

SMR:

Q05793

KEGG:

mmu:15530

String:

Q05793

UniGene:

Mm.273662

Uniprot:

Q05793

FOR

ELISA Kit for Mouse HSPG

Cat.:

E0565m

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Mouse HSPG

Cat.:

E0565h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Mouse HSPG

Cat.:

U0565m

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Mouse HSPG

Cat.:

U0565h

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Mouse HSPG

Cat.:

P0565Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse HSPG

Cat.:

P0565Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse HSPG

Protein for Mouse HSPG

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The complete sequence of perlecan, a basement membrane heparan sulfate proteoglycan, reveals extensive similarity with laminin A chain, low density lipoprotein-receptor, and the neural cell adhesion molecule."
Noonan D.M. , Fulle A. , Valente P. , Cai S. , Horigan E. , Sasaki M. , Yamada Y. , Hassell J.R.
J. Biol. Chem.266:22939-22947(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Melanoma.
2.

"Identification of cDNA clones encoding different domains of the basement membrane heparan sulfate proteoglycan."
Noonan D.M. , Horigan E.A. , Ledbetter S.R. , Vogeli G. , Sasaki M. , Yamada Y. , Hassell J.R.
J. Biol. Chem.263:16379-16387(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 940-1601 AND 1870-2600;PARTIAL PROTEIN SEQUENCE
3.

"Structural properties of recombinant domain III-3 of perlecan containing a globular domain inserted into an epidermal-growth-factor-like motif."
Schulze B. , Mann K. , Battistutta R. , Wiedemann H. , Timpl R.
Eur. J. Biochem.231:551-556(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL PROTEIN SEQUENCE
4.

"Perlecan is essential for cartilage and cephalic development."
Arikawa-Hirasawa E. , Watanabe H. , Takami H. , Hassell J.R. , Yamada Y.
Nat. Genet.23:354-358(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION
5.

"BMP-1/Tolloid-like metalloproteases process endorepellin, the angiostatic C-terminal fragment of perlecan."
Gonzalez E.M. , Reed C.C. , Bix G. , Fu J. , Zhang Y. , Gopalakrishnan B. , Greenspan D.S. , Iozzo R.V.
J. Biol. Chem.280:7080-7087(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEOLYTIC PROCESSING
6.

"WARP is a novel multimeric component of the chondrocyte pericellular matrix that interacts with perlecan."
Allen J.M. , Bateman J.F. , Hansen U. , Wilson R. , Bruckner P. , Owens R.T. , Sasaki T. , Timpl R. , Fitzgerald J.
J. Biol. Chem.281:7341-7349(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH VWA1
7.

"Perlecan is critical for heart stability."
Sasse P. , Malan D. , Fleischmann M. , Roell W. , Gustafsson E. , Bostani T. , Fan Y. , Kolbe T. , Breitbach M. , Addicks K. , Welz A. , Brem G. , Hescheler J. , Aszodi A. , Costell M. , Bloch W. , Fleischmann B.K.
Cardiovasc. Res.80:435-444(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION
8.

"The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation."
Gundry R.L. , Raginski K. , Tarasova Y. , Tchernyshyov I. , Bausch-Fluck D. , Elliott S.T. , Boheler K.R. , Van Eyk J.E. , Wollscheid B.
Mol. Cell. Proteomics8:2555-2569(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-89; ASN-2336; ASN-3098 AND ASN-3154
tissue: Myoblast.
9.

"Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."
Wollscheid B. , Bausch-Fluck D. , Henderson C. , O'Brien R. , Bibel M. , Schiess R. , Aebersold R. , Watts J.D.
Nat. Biotechnol.27:378-386(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-2336 AND ASN-3098
10.

"Crystal structure and mutational analysis of a perlecan-binding fragment of nidogen-1."
Hopf M. , Gohring W. , Ries A. , Timpl R. , Hohenester E.
Nat. Struct. Biol.8:634-640(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 1761-1858 IN COMPLEX WITH A NIDOGEN FRAGMENT

Product Feedback Wall

* Email:
*Comments: